Which type of parasite is not sensitive to pyrantel tartate?

Pyrantel tartrate is an anthelmintic medication that is effective primarily against certain types of roundworms, such as ascarids and strongyles, and is commonly used in treating horses for these parasites. However, it is not effective against bot larvae, which are the immature forms of bot flies.

Bots, specifically, are not part of the typical helminths that pyrantel works against, as they have a different life cycle and biology. Instead, bot larvae develop in the stomach and intestines of horses, and their treatment typically requires a different class of dewormers, such as ivermectin or moxidectin, which target the specific type of parasites represented by bot flies.

In contrast, pyrantel is effective against roundworms and potentially effective against other types of helminths, but it does not address tape worms. This distinct mechanism of action is why bot larvae are identified as the type of parasite not sensitive to pyrantel tartrate.