What disease is characterized by high temperature and nasal discharge after the second or third day, along with swollen lymph nodes?

Strangles is characterized by a respiratory infection in horses that is typically caused by the bacterium Streptococcus equi. One of the key features of this disease is the onset of high fever and nasal discharge, often appearing after the first few days of infection. The febrile response is due to the body's immune reaction to the bacteria.

Additionally, swollen lymph nodes, particularly those located under the jaw (submandibular lymph nodes), are a notable sign of strangles. As the bacteria invade and proliferate, these lymph nodes can become significantly enlarged and painful, eventually leading to abscess formation.

While the other diseases listed may have some overlapping symptoms—such as respiratory signs—strangles is uniquely identified by the specific combination of high fever, nasal discharge after a couple of days, and notably swollen lymph nodes. This distinct presentation makes strangles easily distinguishable from other equine illnesses like equine influenza, West Nile Virus, or Rhino pneumonia, each of which has its own specific clinical features and progression patterns.